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Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and inactivate penicillin. They are used
(-lactamases of the penicillinase type or with D-alanine carboxy- peptidases. evolutionary origin different from that of the serine penicillinases and thus
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pen·i·cil·lin·ase (p n -s l -n s ). n. Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and
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The penicillinase from an Escherichia coli strain harboring an R factor RGN823 was purified and its properties were compared with those of a known type I
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CBAP is hydrolyzed by the Bacillus penicillinase, but as
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MICROBIAL RESISTANCE TO PENICILLIN. 54 7. 17. Roseliberg, A., HOW^, C., Chargaff, E., ibid.,. 18. Himwich, H. E., SC~Y~CC,. 1958, v127, 59. 1956, ~ 1 7 7
If the bacterium produces the enzyme β-lactamase or the enzyme penicillinase, the enzyme will hydrolyse the β-lactam ring of the antibiotic, rendering the
Penicillinase is an enzyme produced by certain bacteria which inactivates penicillin by hydrolzing the amide bond in the beta-lactam ring.
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pen·i·cil·lin·ase (pĕn ĭ sĭlʹĭ nās ) n. Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and
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penicillinase ( ) n. Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and.
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Penicillinase2 is an enzyme specific for its substrate penicillin. Its inactivating action against penicillin has been utilized for years in the clinical laboratory in
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Penicillinase Listen. noun. Penicillinase n. (Bioch.) An enzyme which destroys the antibacterial activity of penicillin by hydrolyzing the amide bond in the
penicillinase production were investigated for their susceptibility to methitillin Nineteen strains of S. aureus which existed in both a penicillinase producing and
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often owe their resistance to their inducible penicillinase. Abraham and Chain. ( 1940) showed clearly that a specific enzyme, penicillinase, was involved in the
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Acronym Finder: PPNG stands for Penicillinase-Producing Neisseria Gonorrhea. This definition appears very rarely.
(1969) Peyru et al. Journal Of Bacteriology. A series of plasmids harbored by naturally occurring penicillin-resistant strains of Staphylococcus aureus were
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The effects of subminimal inhibitory concentrations of kanamycin, amikacin and gentamicin on the production of penicillinase by Staphylococcus aureus were
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Penicillinase production was tested on all samples by iodometric method[10] The penicillinase production was positive in 99 (90%) strains by
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produces coagulase, ferments mannitol, and elaborates penicillinase were did not ferment mannitol, 16 did not elaborate penicillinase, and 15 were untyp-
Determination of MICs using light inocula fails to detect the destructive effect of penicillinase on the antibiotic. This was, however, demonstrated reproducibly by
In King County, Washington, penicillinase-producing Neisseria gonorrhoeae 268 penicillinase-producing N gonorrhoeae isolates tested, 159 (59%) be-
veillance for cases of infection due to penicillinase-producing Neisseria gonorrhoeae One hundred ninety-one cases of penicillinase-producing gono-
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THE APPLICATION of the enzyme penicillinase (Neutrapen) as a therapeutic agent in the treatment of penicillin reactions has been reassuring to the patient as
5-Methyl tryptophan was found to be an efficient inducer of penicillinase synthesis in Staphylococcus aureus. Addition of actinomycin D or tryptophan to the
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Antistaphylococcal penicillinase sera were prepared using cell-free staphylo- sigl~ihcant difference in the neutralizing ability of anti-B. cereus penicillinase
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penicillinase denotes p-lactamase preparations that catalyze the hydrolysis of the reactor with penicillinase covalently bonded to derivatized. (sililated) glass
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Publication » Constitutive penicillinase formation in Staphylococcus aureus owing to a mutation unlinked to the penicillinase plasmid.
bound penicillinase was localized at or near the cell surface. The P-penicillinase However, the y-penicillinase was tightly bound to the cytoplasmic membrane.
Dr. Kim's strategy involves the use of small, specific nucleic acid fragments he has labeled “aptamers” as penicillinase inhibitors so that the
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strains of staphylococcal organisms that elaborate the penicillin-inactivating enzyme penicillinase (beta-lactamase) and thereby resist the bactericidal action of
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Rush, Mark G. and Gordon, C. N. and Novick, Richard P. and Warner, Robert C. ( 1969) Penicillinase Plasmid DNA from Staphylococcus aureus
PENICILLINASE hydrolyses the ,&lactam ring in 6-aminopenicillanic acid occurrence of penicillinase producing bacteria has prompted attempts to synthesise
Penicillinase and the convulsant action of penicillin. Michael J. Gutnick, D.V.M., and David A. Prince, M.D.. PENICILLIN. HAS BEEN RECOGNIZED as a convul-
Conditions suitable for induced formation and secretion of penicillinase (EC 3.5. 2.6) in protoplasts of Staphylococcus aureus were determined. No requirement
RAPID IDENTIFICATION OF PENICILLINASE-PRODUCING NEISSERIA GONORRHOEAE BY DETECTION OF BETA-LACTAMASE IN URETHRAL EXUDATES.
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penicillinase. penicillinase is a valid word in this word list. For a definition, see the external dictionary links below. The word "penicillinase" uses 13 letters:
At neutral pH, the rate of penicillinase synthesis by staphylococci declines gradually after removal of free inducer, while at pH 5.4 enzyme formation is generally
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Definition of the term Penicillinase: A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-.
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A strain of Streptococcus faecalis with plasmid-mediated penicillinase production was studied further. Partially purified penicillinase from the S. faecalis strain
An intensified prevention program has controlled the first outbreak of penicillinase-producing Neisseria gonorrhoeae (PPNG) infections in a
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the NH2 terminus of themembrane penicillinase because they can be completely blocked the accumulation of penicillinase in the plasma mem- brane, and
Worldwide: Cases of infection caused by penicillinase-producing Neisseria gonorrhoeae (PPNG) have now been detected in 16 different countries - Australia,
Induction of penicillinase (beta-lactamase) in Bacillus licheniformis 749 by 2-(2'- carboxyphenyl)-benzoyl-6-aminopenicillanic acid (CBAP) was
The penicillinase determinants on the 22-MDa plasmid have been found to transpose to the chromosome and from the chromosome to an 18-MDa plasmid
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PENICILLINASE-PRODUCING GONOCOCCI IN LIVERPOOL. By - A. Percival, J.E. Corkill, O.P. Arya, J. Rowlands, C.D. Alergant, Elizabeth Rees, E.H. Annels.
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penicillinase-resistant antibiotic - Meaning and definition.
The instance of microorganisms developing antibiotic resistance seems to be a never-ending process. There are several reasons why
5.1.1.2 Penicillinase-resistant penicillins. Most staphylococci are now resistant to benzylpenicillin because they produce penicillinases. Flucloxacillin, however
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The penicillinase from an Escherichia coli strain harboring an R
Modified ELISA, using penicillinase or urease conjugates, was compared with the For penicillinase, its penicillin substrate was compared for use with three
SPECTINOMYCIN-RESISTANT PENICILLINASE-PRODUCING NEISSERIA GONORRHOEAE. By - WinstonA. Ashford, HarveyJ.U. Adams, StevenR. Johnson
Penicillinase - definition. Other names beta-Lactamase I; gamma Penicillinase; beta-Lactamase, AER-I; Lactamase RP4, beta; beta Lactamase I; Lactamase III
Preventing penicillinase production in antibiotic sensitive Bacillus subtilis. ( Section 1): Factors contributing to penicillin sensitivity and viability of Sarcina lutea in
Modified Substrate Specificity of Cell-bound Penicillinase. Authors: Ron-Zenziper , Eliora; Citri, Nathan. Affiliation: AA(Department of Bacteriology, Hebrew
CHARLES, BG and RAWAL, BD (1977) ACTION OF CAFFEINE AND THEOPHYLLINE ON STAPHYLOCOCCAL PENICILLINASE SYNTHESIS.
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The kinetics of penicillinase induction in Bacillus cereus 569
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Some of the factors influencing synthesis of penicillinase by M. pyogenes are described. Adaptive formation of the enzyme by this organism was not observed
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Penicillinase susceptibility divided the antibiotics into two groups: one Nineteen strains of S. aureus which existed in both a penicillinase producing and a
Inhibitors of penicillinase are therefore of potential clinical
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Key Words: N. gonorrhoeae, penicillinase producing N. gonorrhoeae, The report of the isolation of penicillinase-producing Neisseria gonorrhoeae (PPNG) in
A curve calculated from model B (n = 3) is shown in Fig. 1. This curve fits the ex- perimental points substantially better than those from models A2 and A3 (all
The pH optimum for 6-aminopenicillanic acid hydrolysis by both staphylococcal and Bacillus cereus penicillinase is sharper and lower than for benzylpenicillin.
NAD' system were synthesized for a group of staphylococcal penicillinase resistant heterocyclic ring is not enough to confer penicillinase re- sistance, other
Transmission of spectinomycin-resistant penicillinase-producing Neisseria gonorrhoeae (PPNG) has been documented for the first time.
WebMD provides information about interactions between warfarin Oral and PENICILLINASE RESISTANT PENICILLINS.
The cell-bound and exocellular penicillinases of B. licheniformis 749/C are resistant to trypsin and chymotrypsin. The production of penicillinase sensitive to
Unbound MEDLINE/PubMed | Penicillinase-producing
Define penicillinase. What is penicillinase? penicillinase meaning, synonyms and audio pronunciation and more by Oxford Dictionaries Online (World English)
Scientific Experts, Genomes and Genes, Publications, Research Grants, Research Topics about penicillinase.
Enzyme, Penicillinase (β-lactamase type I). EC, 3.5.2.6. Source, Bacillus cereus 569H. Catalyzed reaction, Hydrolysis of benzylpenicillin. Known substrates
Polyclonal Antibody against Penicillinase for use in ELISA, Immunohistochemistry, Western Blot, Dot blot.
[edit] Noun. penicillinase (countable and uncountable; plural penicillinases). Wikipedia has an article on: Penicillinase · Wikipedia. (biochemistry) A specific type
Good penicillinase producers are Bact. coli, the Bacillus subtilis-mesentericus group, Bacillus anthracis and Staphylococci. Both intra- and extracellular
Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.
"penicillinase-resistant antibiotic" definition: a form of penicillin that isn't rendered inactive by penicillinase. Type of: penicillin. +References.
Dictionary; Thesaurus; Spanish; Medical; Concise Encyclopedia. penicillinase. pen·i·cil·lin·ase. noun \-ˈsi-lə-ˌnās, -ˌnāz\. Definition of PENICILLINASE
definition of penicillinase - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic.
"Penicillinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged
A novel plasmid pXP102-3 which is constructed from Aeromonas sp. No. 212 chromosomal DNA fragment coding for production of xylanase and a vector
19, 1988, Susceptibility of penicillinase-producing and non-penicillinase- producing strains of Neisseria gonorrhoeae isolated in Durban, South Africa, to 15
Importance of penicillinase production for activity of penicillin alone or in combination with sulbactam in experimental endocarditis due to methicillin- resistant
A novel plasmid pXP102-3 which is constructed from Aeromonas sp. No. 212 chromosomal DNA fragment coding for production of xylanase
The present paper describes the use of penicillinase, an enzyme specific for the inactivation of penicillin. Patients with penicillin reactions were given
[1], "Penicillinase from Bacillus licheniformis: nucleotide sequence of the gene and implications for the biosynthesis of a secretory protein in a
beta lactamase and penicillinase are the same thing and the second is a very good question. as far as i remember augmentin is not used when
A culture method for the isolation and identification of penicillinase (1- lactamase) -producing Neisseria gonorrhoeae (PPNG) was evaluated in the Philip-
Optimum polytyramine-penicillinase (PTy-PNCnase) films for potentiometric tyramine, 37 U/mL penicillinase, 0.01 M KNO3, and 3 mM penicillin with an
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a penicillinase-resistant form of penicillin (trade name Nafcil) used (usually in the form of its sodium salt) to treat infections caused by penicillin-resistant strains
of penicillinase-resistant penicillins against clinical isolates of penicillinase- resistant penicillin during gentamicin administra- tion. Addition of
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This fragment was fused to the distal ends of either the penicillinase (penP) gene By using plasmid pMB9, penicillinase genes (penP and penI) from both the
Rolinson 196I), an enzyme quite distinct from the classic 'penicillinase' which bility that this original 'penicillinase' of Abraham & Chain might have really been
Category:GO:0033250 ! penicillinase activity. From GONUTS. Jump to: name: penicillinase activity namespace: molecular_function
Penicillinase-producing strains of S. aureus were isolated from the upper respiratory tract of 28% of a group of children presenting with signs or symptoms of
Penicillinase, next to catalase, has one of the highest turnover numbers known ( 1.48 Rate of hydrolysis of benzyl penicillin by penicillinase from B. subtilis
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Accession number;00A0101933. Title;Molecular Biological Properties of Penicillinase Within Ampicillin Resistant Pasteurella Piscicida. Author; ISHIDA AKIO
The following semisynthetic penicillins, which are resistant to penicillinase,. should be used only The cephaloporins resist the action of penicillinase. They are
Cloxacillin in dogs, cats and other pets: the indications for use, side effects, contraindications, drug or food interactions, toxicity, and signs of an overdose.
The membrane penicillinase ofBacillus licheniformis 7491. C differs from the brane penicillinase to the exo form is probably carried out by a specific
The activity of penicillin, alone and in combination with sulbactam, against a heterogeneously methicillin-resistant, penicillinase-producing clinical isolate of
SUMMARY: A penicillinase-positive variant was isolated from a penicillinase- negative strain of Escherichia coli during 'training' towards ampicillin resistance.
Production and purification of the extracellular penicillinase from Bacillus cereus, NRRL The increasing application of penicillinase to testing penicillin sterility
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the penicillinase gene (via a plasmid); then the methicillin resistance gene mec. Mec: Originated in S. scuiri another species of Staphylococcus;
With clavulanic acid phenyl, semi-synthetic, penicillinase-sensitive, xpenicillinase producing staphylococcus aureus may bio- mechanism Amoxicillin they
by the penicillinases of gram-negative bac- teria but may exhibit penicillinase- sensitive drugs has been clearly cases when the penicillinase-resistant peni-
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