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Monoamine oxidase inhibitors (MAOIs) .. group of drugs, once the mainstay of treatment, includes tricyclic (tertiary amines amitriptylineSome Trade Names
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The third group of drugs are the Monoamine Oxidase Inhibitors (MAOI) which block Imipramine, the first of the tricyclics, is still widely used as is amitriptyline
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Examples of MAOIs include phenelzine (Nardil) and tranylcypromine (Parnate). Examples of tricyclic antidepressants are amitriptyline (Elavil), protryptyline
Amitriptyline (Elavil); Clomipramine (Anafranil); Desipramine (Norpramin) MAOIs (monoamine oxidase inhibitors) are the oldest class of antidepressants.
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Amitriptyline protects patients on MAOIs from tyramine reactions. Kline NS, Pare M, Hallstrom C, Cooper TB. PMID: 7174870; [PubMed - indexed for MEDLINE]
Not to be given concomitantly with MAOIs; discontinue MAOI therapy at least 14 days before starting amitriptyline. Acute recovery phase following MI, acute CHF.
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