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High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL Study: a randomized controlled trial.
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Comparison of efficacy and safety of atorvastatin (80 mg) to simvastatin (20 to 40 the Incremental DEcrease through Aggressive Lipid Lowering [IDEAL] study).
Comparison of Efficacy and Safety of Atorvastatin (80 mg) to Simvastatin (20 to DEcrease through Aggressive Lipid Lowering [IDEAL] Study)
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Economic evaluation of high-dose (80 mg/day) atorvastatin treatment compared Decrease in End-Points Through Aggressive Lipid-Lowering (IDEAL) trial.
Title: High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial
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High-dose atorvastatin vs. usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial.
High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction. The IDEAL study: A randomized controlled trial.
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High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial. JAMA.
High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the. IDEAL study: a randomized controlled trial.
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dose produces a higher risk reduction.4 The Ideal. Study, which compared simvastatin non-aggressive dosing with 20 mg versus atorvastatin 80 mg, also
'IDEAL' study atorvastatin 80mg (%LDL 55%) compared with simvastatin. 20mg ( %LDL 35%) failed to reach the primary prespecified endpoint with no mortality
IDEAL: Study Design: High-dose statin therapy with atorvastatin in IDEAL, TNT, and PROVE IT-TIMI 22 lowered LDL cholesterol to 81, 77, and 62 mg/dL,
High-dose Atorvastatin vs Usual-dose Simvastatin for Secondary Prevention After Myocardial Infarction The IDEAL study: A Randomized Controlled Trial By:
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In the IDEAL* trial, 8888 patients (aged ≤ 80 years) with prior Over a median of 4.8 years, atorvastatin 80 mg/day prevented one in five
dose statins (atorvastatin 80 mg) versus usual sta- cent studies, such as the ones reported in Treating events) the IDEAL trial showed a significant 13%
9.0%) (Collaborative Atorvastatin Diabetes Study ("CARD")--Lancet 364:685, . ( "IDEAL") trial randomized 8888 pts < 80yo with h/o prior MI to atorvastatin
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Points Through Aggressive Lipid Lowering (IDEAL) Study Group. High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial
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Results. In the IDEAL trial, compared with patients taking simvastatin 20 to 40 mg daily, patients receiving atorvastatin. 80 mg daily had their relative risk of a first
Evidence base for atorvastatin 80mg - Prove-IT /TIMI 22 trial, MIRACL study, IDEAL study. Aim of the audit was o evaluate the appropriateness of prescribing of
In IDEAL (see [#section-3.5 CLINICAL PHARMACOLOGY, Clinical Studies])
A similar result was observed in the IDEAL trial, in which the effects of low-dose simvastatin were compared with the effects of high-dose atorvastatin.7 The
Fortunately this hypothesis has already been examined in the IDEAL study, but that RCT did not support it. IDEAL compared atorvastatin 80mg
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The IDEAL (Incremental Decrease in End Points Through Aggressive Lipid Lowering) study compared high-dose atorvastatin (80 mg daily) and 'usual-dose'
Comparison of Efficacy and Safety of Atorvastatin (80 mg) to Simvastatin through Aggressive Lipid Lowering [IDEAL] Study) - Cardiovascular
This editorial refers to 'Cost-effectiveness of high-dose atorvastatin . In the IDEAL trial, there was no significant difference in mortality
Tikkanen MJ; IDEAL Study Group. Comparative effect of atorvastatin (80 mg) versus simvastatin. (20 to 40 mg) in preventing hospitalizations for heart failure in
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Journal Club High-dose Atorvastatin vs Usual-dose Simvastatin for Secondary Prevention After Myocardial Infarction The IDEAL study: A
"These data suggest the benefit of intensive treatment with Lipitor 80mg in very high-risk heart attack IDEAL was an investigator-led trial sponsored by Pfizer.
Similarly, in the IDEAL trial a trend toward an increase in new-onset T2DM was observed in the atorvastatin 80 mg group (HR: 1.16, 95% CI: 0.96 to 1.40,
IDEAL Study: Secondary End Points for statin therapy were randomly assigned to receive atorvastatin 80 mg/d (n=4439) or simvastatin 20 mg/d (n=4449).
seen in the AFCAPS/TexCAPS trial which demonstrated that the best overall . hypertensive patients (14) and the Collaborative Atorvastatin Diabetes Study
people.4 More recent studies have deter- mined that . the Collaborative Atorvastatin Diabetes. Study .. tion: the IDEAL study: a randomized controlled trial.
IDEAL Trial Overview 1. ♦ a multi-center prospective randomized open-label, blinded end-point trial to determine lipid lowering effects of high dose atorvastatin
RCT (randomized controlled trial) · Statins · Primary prevention
Learn about LIPITOR® (atorvastatin calcium) and proven CV event risk reductions in MI ||Trials include ASCOT-LLA,8 CARDS,6 IDEAL,14 PROVE IT ( a study
In the Incremental Decrease in End Points Through Aggressive Lipid-Lowering ( IDEAL) study, treatment with atorvastatin 80 mg/day was associated with an
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Treating to New Targets (TNT) study and by 80 mg/day atorvastatin
a Thrombolysis In Myocardial Infarction Study Group, Cardiovascular Division, . simvastatin 20 mg titrated to 40 mg versus 80 mg atorvastatin in the IDEAL trial.
Lowering (IDEAL) study, which compared a 80 mg/day regimen of atorvastatin against a 20 mg or 40 mg/day regimen of simvastatin, was “consistent with the re-
High-Dose Atorvastatin vs Usual-Dose Simvastatin for Secondary Prevention After Myocardial Infarction. The IDEAL Study: A Randomized Controlled Trial
The IDEAL study: a randomized controlled trial. JAMA 2005;294:2437-45. 9. Schwartz GG et al. Effects of atorvastatin on early recurrent ischemic events in
The Incremental Decrease in End Points Through Aggressive Lipid Lowering ( IDEAL) study compared the effects of intensive (80 mg/d of atorvastatin) vs
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High-Dose Atorvastatin vs Usual-Dose Simvastatin for Secondary Prevention After Myocardial Infarction. The IDEAL Study: A Randomized
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High-dose atorvastatin versus usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized
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Another study comparing high and low doses of atorvastatin in in End Points Through Aggressive Lipid Lowering (IDEAL) study examined
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[34072] The. IDEAL trial reported no significant difference in rate of all-cause mortality or first coronary event in. Atorvastatin. Lipitor®. Print
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IDEAL Trial: Background aggressive lipid lowering with 80 mg per day of atorvastatin provided more protection from death and cardiovascular events than 40
The authors of the IDEAL trial did not comment on this alarming finding after atorvastatin treatment.12 If true, and if the five cases observed in the TNT trial (50
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High-dose atorvastatin vs usual-dose simvastatin lot secondary prevention after myocardial infraction: the IDEAL study: a randomized controlled trial, JAMA.
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IDEAL was a study of high dose atorvastatin versus standard dose simvastatin in patients with stable CHD. As in the original IDEAL trial,
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The trial, Incremental Decrease in Endpoints through Aggressive Lipid Lowering (IDEAL), was funded by the manufacturer of atorvastatin.
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A comparative study of atorvastatin and simvastatin as simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a
Methods and results The IDEAL trial showed that high-dose treatment with atorvastatin was associated with fewer non-fatal myocardial infarctions (MI) or
Pedersen TR et al, High-dose atorvastatin vs usual-dose epilepsy for secondary positiveness after theoretical zoster: the IDEAL study: a scrotal
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Contains details of High-dose atorvastatin vs usual dose simvastatin for secondary prevention after myocardial infarction - The IDEAL study A randomized
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Caduet(): CADUET (amlodipine and atorvastatin) is indicated in patients for whom In IDEAL (see CLINICAL PHARMACOLOGY, Clinical Studies) involving
as a negative outcome trial, atorvastatin had a beneficial effect on secondary ( IDEAL) trial, contributing to a negative result.20 In the Assess- ment of LEscol in
This ARR can be compared to that resulting from a major clinical trial such as IDEAL, which compared 80 mg atorvastatin to 20 mg simvastatin in secondary
Through Aggressive Lipid Lowering. (IDEAL) study, was that intensive low- ering of LDL-C with atorvastatin at the highest recommended dose
High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction. The IDEAL Study: a randomized controlled trial. JAMA.
In the Incremental Decrease in Endpoints Through Aggressive Lipid Lowering Study (IDEAL), treatment with LIPITOR 80 mg/day was compared to treatment with
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Cholesterol drug atorvastatin led to higher incidence of new-onset type 2 diabetes mellitus in three studies. Though blood glucose was still best
Economic evaluation of intensive atorvastatin treatment versus standard simvastatin treatment in Canada based on the IDEAL trial. M. Wagner1
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Perhaps the best study conducted to date was that of Koh et al.. They randomized 220 patients to placebo, atorvastatin 10, 20, 40 or 80 mg (44 per group).
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The other RCT, an open-label study with blinded endpoint assessment (the IDEAL study) compared atorvastatin 80 mg daily with simvastatin 20 mg daily
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