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Influence of cue-conditioning on acquisition, maintenance and relapse of cocaine intravenous self-administration. Deroche-Gamonet V, Piat F, Le Moal M,
The Index page for the reference article: Martellotta MC, Balducci C, Fattore L, Cossu G, Gessa GL, Pulvirenti L, Fratta W
An experience with Cocaine (IV). 'Tracks in the Snow' by Typhon.
Particularly dangerous forms of polydrug abuse, such as the combined use of heroin and cocaine intravenously, remain a major problem in
Intravenous injections of cocaine HCl are habit-forming because, among their many actions, they elevate extracellular dopamine levels in the terminal fields of
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tion between cocaine use and endocarditis in intravenous drug users. Materials and Methods. DATA COLLECTION. All hospitalizations at the medical services
The hydrochloride salt, or powdered form of cocaine, dissolves in water and, when abused, can be taken intravenously (by vein) or intranasally (in the nose).
associated with acute cocaine intoxication requires treatment with sublingual nitroglycerin or intravenous phentolamine. ß-Blockers and labetalol are
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Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus
Otherwise known as shooting, slamming, banging, blasting, or mainlining, intravenous injections usually result in a much more rapid availability of the drug into
Psychiatry Research, Volume 77, Issue 1, Pages 35-42, 16 January 1998, Authors:Bankole Johnson; Dennis Overton; Lynda Wells; Paul Kenny; David
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Bacterial endocarditis may accompany cocaine use if the drug was used intravenously. For unknown reasons, cocaine use has been observed
Prior studies in experimental canine models have demonstrated that intravenous cocaine administration causes myocardial depression. The purpose of the
COCAINE. Cocaine and crack are toxic, addictive, psychoactive substances that . For intravenous (IV) cocaine users, there is increased risk of hepatitis, HIV
Gamma-Hydroxybutyric Acid Decreases Intravenous Cocaine Self-Administration in Rats - Relation to the development of experimental
Abstract. To examine whether recent intravenous use of cocaine might be associated with increased risk of human immunodeficiency virus type 1 (HIV) infection,
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Finally, this study sought to contribute to the literature on genetic differences in intravenous cocaine self-administration behavior by extending observations
Biological Psychiatry, Volume 24, Issue 8, Pages 865-885, December 1988, Authors:Michael A. Sherer.
In the following experiments, we examined the relationship between sensitization induced by social defeat stress and intravenous cocaine self-administration in
of cocaine hydrochloride in 2 per cent. solution introduced intravenously. Cerebration was normal except for a restless inability to keep the
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More specifically, the present experiments focused on evaluating the intravenous cocaine self-administration in mice of two strains under different schedules of
The role of corticosterone in cocaine reinforcement was investigated in rats exposed to prior to the initiation of testing for intravenous cocaine self- administration.
The patient endorsed daily use of intravenous cocaine mixed with 400 mg—800 mg of quetiapine. Quetiapine was surreptitiously diverted from
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Cocaine kinetics were studied in four subjects after intravenous and KEY WORDS Cocaine Pharmacokinetics Intranasal cocaine Intravenous cocaine
In lay language, Cocaine, AIDS, and Intravenous Drug Use presents what works and what doesna (TM)t work in counseling drug dependent persons. Those in
(2002) Ikegami et al. Pharmacology Biochemistry and Behavior. Read by researchers in: 75% Psychology, 25% Biological Sciences. Evidence suggests that
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Conclusions Intravenous cocaine induces activation of individual circulating platelets; this effect is not reproduced by infusion of norepinephrine at doses
Journal of the American Academy of Dermatology, Volume 16, Issue 2, Pages 462-468, February 1987, Authors:MC Heng; G Haberfeld.
Cocaine pharmacodynamics after intravenous and oral administration in rats: relation to pharmacokinetics. (PMID:10435404). Abstract; Citations List of citations
in the maintenance of intravenous cocaine self-administration in rats was investigated using the centrally active, small molecule CRH1 receptor antagonist
Publication » Effects of chlordiazepoxide on intravenous cocaine self- administration in rats.
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Question - why do you vomit sometimes after intravenous cocaine use. Find the answer to this and other Medical questions on JustAnswer.
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IV drug use is a relatively recent phenomenon arising from the invention of re- usable syringes and the synthesis of chemically pure morphine and cocaine.
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Subjective and Physiological Effects of Intravenous Nicotine and Cocaine in. Cigarette Smoking Cocaine Abusers. Jones, H.E., Garrett, B.E., and Griffiths, R.R.
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Crack cocaine acts almost as fast as cocaine injected intravenously. Heavy regular users and people who inject the drug intravenously or smoke it are most
Intravenous cocaine produced robust dose-related increases in subjective and reinforcing effects; intravenous effects of nicotine, cocaine, and caffeine as well
RESULTS: Patients most commonly used cocaine intravenously (49%), but freebase or crack use was also common (23.3%). Concomitant abuse of other
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Cocaine is presently the most abused major stimulant in America. crystalline white powder can be dissolved in water and used intravenously ("slammed").
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The dependency for injecting cocaine is 4.5 times more intense than snorting it. That means the dependency for injecting cocaine is also 1.5 times
The present study investigated the effect of acute intravenous cocaine administration on endothelium-dependent vasodepressor responses to acetylcholine in
The patient was admitted to a New York hospital with symptoms of botulism several days after attempting to inject cocaine intravenously.
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Gamma-hydroxybutyric acid decreases intravenous cocaine self-administration in rats. (PMID:9512074). Abstract; Citations List of citations in UKPMC which this
The effect of the CB1 cannabinoid receptor agonist WIN 55212-2 on intravenous cocaine self-administration (IVSA) in rats was evaluated. Male Long Evans rats
4: Fiancette JF, Balado E, Piazza PV, Deroche-Gamonet V. Mifepristone and spironolactone differently alter cocaine intravenous self-administration and
Gene-environment interactions in vulnerability to cocaine intravenous self- administration: a brief social experience affects intake in DBA/2J but
Interactions Between Intravenous (IV) Cocaine and Lofexidine. This study has been terminated. First Received on June 17, 2010. Last Updated on April 4, 2011
of the intravenous administration of 48 mg of cocaine (a typical “street” dose) on the occu- pancy of dopamine 2 receptors in the putamen of 11 self-identified
Cocaine has a relatively short half-life in the plasma and in the brain. When administered intravenously (IV) to humans, the half-life is in the range of 16 to 87
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crack cocaine delivers an intensity of pleasure beyond the bounds of normal Normally, only the intravenous route of administration could be expected to
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When a person is under the influence of a stimulant such as cocaine, their pupils will appear very enlarged. If a person is using cocaine intravenously, there will
Eight mixed-breed fetal sheep comprised the fetal group; their responses to a 2 mg/kg iv cocaine injection were reported previously (14).
Studies show that healthy volunteers blood level of cocaine after smoking paste raises as rapidly as after intravenous injection of the drug. Combining cocaine
tient methadone withdrawal program without success. Two days before admission, he began injecting cocaine intravenous- ly, with at least five injections for
American Journal of Obstetrics & Gynecology, Volume 170, Issue 5, Pages 1416- 1420, May 1994, Authors:Mark A. Morgan, MDa; Richard A. Wentworth, PhDb;
diminish the rewarding effects of intravenous cocaine and produce patterns . rison of the arterial kinetics of smoked and intravenous cocaine. In: Harris, L. (Ed. )
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intravenous (IV) injections of cocaine (.75 mg/kg) or saline immediately or Finally, an IV priming injection of cocaine was administered to reinstate the
2063-2071 Pergamon Press Printed in the U.S.A. LACK OF CARDIOVASCULAR TOLERANCE DURING INTRAVENOUS COCAINE INFUSIONS IN HUMAN
Cocaine esterase prevents cocaine-induced toxicity and the ongoing intravenous self-administration of cocaine in rats. Collins GT, Brim RL,
Similar to intravenous cocaine, intravenous heroin also increases the risk of endocarditis, a condition in which bacteria enter the blood and
Title: Aminergic influences on intravenous cocaine self-administration by rhesus monkeys. Authors: Wilson, Marvin C. Schuster, Charles R. Issue Date: 1974
Temporal determinants of intravenous cocaine self-administration in rhesus monkeys'. R.S. Mansbach and R.L. Balster. Department of Pharmacology and
We tested the hypothesis that intravenous cocaine, in doses commonly self- administered in nonmedical settings, causes acute myocardial ischemia and left
It can also be liquefied and injected intravenously. Cocaine has been used for both recreational and scientific purposes for many centuries. But as its use
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Trabecular Outflow Facility and Formation Rate of Aqueous Humor During Intravenous Cocaine or Lidocaine in Rabbits. Alan A. Artru, MD. Department of
Intravenous Cocaine Decreases Cardiac Vagal Tone, Vagal Index (Derived in Lorenz Space), and Heart Period Complexity (Approximate Entropy) in Cocaine
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To test this, rats were trained to run an alley for a single intravenous dose of either cocaine. (0.5-2.0 mg/kg) or an equimolar dose of CE (0.75-2.88 mg/kg).
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nucleus accumbens increases cocaine intravenous self-administration in the rat. Frédéric Boyer1, Eric Balado2,3, Pier V. Piazza2,3, Jean-Luc Dreyer1 &
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These results indicate that repeated once daily IV injections of cocaine . Interaction of Haloperidol With Chronic IV Cocaine Pretreatment with 0.1, 0.03, or 0.3
Laboratory rats were given unlimited access to intravenous cocaine hydrochloride or heroin hydrochloride. Animals self-administering cocaine quickly
Injecting - Intravenous ( I.V.) Cocaine Use Cocaine & Crack.
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the influence of rate of intravenous cocaine delivery on its ability to induce effects of a fixed dose of intravenous cocaine delivered over 2,. 15, or 60 sec and
(4) This concern is heightened by reports of marked increases in the intravenous use of cocaine.(5,6) Until recently intravenous drug use was considered to be a
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Crack cocaine is being injected - not just smoked - by a significant needles and having unprotected sex, than other intravenous drugs.
Crack cocaine can also be injected intravenously with the same effect as powder cocaine. However, whereas powder cocaine dissolves in water, crack must be
Corticosterone is proposed to modulate cocaine intravenous self-administration ( SA) and cocaine-induced locomotion through distinct receptors, the
Taking a combination of cocaine and heroin through an intravenous injection is known as? Improve. In: Medication and Drugs, Illegal Drugs, Cocaine, Heroin
The rats were trained to self-administer intravenous cocaine (1.0 mg/kg per injection) on a fixed-ratio 1 (FR1) schedule of reinforcement. After stable responding
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Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of therat nucleus
after a single intravenous (i.v.) cocaine self-administration session. demonstrate that a single session of cocaine i.v. self-administration is sufficient to shape rat
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EJ802615 - Intravenous Cocaine Priming Reinstates Cocaine-Induced Conditioned Place Preference.
All of the cocaine injected intravenously is delivered to the circulatory system, versus 20-30% of cocaine that is ingested or inhaled.
Recreationally, coca leaves can be chewed, however, cocaine abusers typically smoke “crack” in a glass pipe or inject the hydrochloride salt intravenously.
Results: Cocaine produced dose-dependent increases on heart rate and blood pressure, with effects lasting longer after oral than IV cocaine. Subjective ratings
We tested the involvement of the GR and the MR in cocaine intravenous SA (1 mg/kg/infusion) and cocaine (20 mg/kg i.p.)-induced locomotor
The disposition of radiolabeled cocaine in humans has been studied after three routes of administration: iv injection, nasal insufflation (ni, snorting), and smoke
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social defeat or amphetamine, and intravenous cocaine self- administration in to nose poke for intravenous cocaine (1.0 mg/kg/inf) during daily 3-h sessions.
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Frontiers | Prenatal IV Cocaine: Alterations in Auditory Information Processing | Frontiers in Child and Neurodevelopmental Psychiatry publishes articles on the
LH increased significantly after both i.v. cocaine and high nicotine cigarette smoking (P < 0.01). These LH increases were significantly correlated with increases
This study compares the behavioral and cardiovascular response to methylphenidate (0.5 mg i.v.) in 10 cocaine abusers and 20 controls. Methylphenidate
BACKGROUND: Cocaine use has been associated with cardiomyopathy and ischemic coronary syndromes. However, the pathophysiological
To examine whether recent intravenous use of cocaine might be associated with studied 2597 active intravenous drug users: 2399 with recent cocaine
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Powdered cocaine is administered via injection (intravenous administration), snorting (insufflation administration), swallowing (oral administration) or gumming
Mifepristone and spironolactone differently alter cocaine intravenous self- administration and cocaine-induced locomotion in C57BL/6J mice. CORD Conference
The effects of i.v. cocaine were examined in individuals maintained on methadone. Sixteen adult methadone-maintained i.v. cocaine users, residing on a clinical
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